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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sage, Eddie | 3B | Morningside Black Cats | 24 | 07/18/2017 | Loveland | USA | Right | Right | 6' 1" | 190 lbs | - |
| Sage, Jason | CF | Amarillo Armadillos | 24 | 10/14/2017 | Hillsboro | USA | Right | Right | 6' 0" | 200 lbs | - |
| Salazar, Danny | 3B | Seattle Airhogs | 20 | 02/06/2022 | Santiago | DOM | Right | Right | 6' 0" | 175 lbs | - |
| Sancez, Jose | SP | Baltimore Jaspers | 25 | 09/02/2016 | Cabo Rojo | PUR | Right | Right | 6' 0" | 190 lbs | - |
| Sanders, Ben | C | Omaha Steaks | 25 | 05/18/2016 | Port St. John | USA | Right | Right | 6' 1" | 200 lbs | - |
| Saunders, Wes | CL | Fresno Orange Sox | 24 | 05/27/2017 | Melbourne | AUS | Left | Left | 6' 1" | 190 lbs | - |
| Schaffer, Dante | LF | Omaha Steaks | 23 | 10/09/2018 | Washington | USA | Left | Left | 6' 4" | 195 lbs | - |
| Schlosser, Dan | 3B | Vung Tau Vipers | 27 | 07/29/2014 | Cedar Mill | USA | Left | Right | 5' 11" | 200 lbs | - |
| Schnorf, Nick | RP | Hamtramck Paczkis | 25 | 01/12/2017 | Norfolk | USA | Right | Right | 6' 4" | 200 lbs | - |
| Schott, Chris | RP | Free Agent | 32 | 03/19/2009 | Atlantic City | USA | Left | Right | 6' 3" | 200 lbs | - |
| Schulte, Jeremy | SP | Hartford Defenders | 21 | 10/02/2020 | Houston | USA | Right | Right | 6' 3" | 185 lbs | - |
| Schuster, Mike | C | Walkerton Scarlet Knights | 27 | 05/12/2014 | Hamilton | USA | Right | Right | 6' 2" | 200 lbs | - |
| Seitz, Geoff | SP | Hamtramck Paczkis | 21 | 05/11/2020 | Vienna | USA | Left | Right | 6' 5" | 190 lbs | - |
| Sepkiechler, Steven | RF | Glendale Skeeters | 23 | 11/27/2018 | Orangeville | CAN | Left | Left | 6' 4" | 200 lbs | - |
| Serafin, Rafael | SS | Walkerton Scarlet Knights | 25 | 12/01/2016 | San Pedro de Macorís | DOM | Right | Right | 6' 0" | 185 lbs | - |
| Sevilla, Willie | SP | Walkerton Scarlet Knights | 22 | 05/09/2019 | Windsor | USA | Right | Right | 6' 7" | 200 lbs | - |
| Sgro, Chris | CF | Grand Rapids Whitecaps | 23 | 03/27/2018 | Trenton | USA | Right | Right | 6' 0" | 180 lbs | - |
| Shanahan, Matt | C | Free Agent | 26 | 02/18/2015 | Bourke | AUS | Right | Right | 5' 10" | 200 lbs | - |
| Shank, Scott | SP | Grand Rapids Whitecaps | 21 | 04/11/2020 | Waukegan | USA | Left | Left | 5' 10" | 170 lbs | - |
| Shatkov, Valerik | RP | Walkerton Scarlet Knights | 25 | 09/17/2016 | Mostyska | UKR | Right | Left | 6' 7" | 200 lbs | - |
| Shaver, Danny | SP | Harrisburg Senators | 25 | 07/24/2016 | Henderson | USA | Right | Right | 6' 1" | 200 lbs | - |
| Short, Jeff | 1B | Fresno Orange Sox | 27 | 02/04/2015 | Honolulu | USA | Switch | Right | 6' 4" | 200 lbs | - |
| Short, Matt | LF | Chesterfield Queens | 23 | 11/09/2018 | International Falls | USA | Right | Right | 6' 4" | 200 lbs | - |
| Simard, Mark | RP | Free Agent | 32 | 03/12/2009 | Bridgeport | USA | Right | Right | 6' 6" | 200 lbs | - |
| Spinks, Jonathan | RP | Grand Rapids Whitecaps | 25 | 11/14/2016 | Perth South | CAN | Left | Left | 5' 9" | 185 lbs | - |
| Staley, Nick | LF | Baltimore Jaspers | 24 | 09/19/2017 | Scranton | USA | Right | Right | 6' 2" | 205 lbs | - |
| Stuart, Nick | LF | Seattle Airhogs | 30 | 04/15/2011 | China Grove | USA | Right | Right | 6' 4" | 200 lbs | - |
| Sweet, Nick | CF | Hartford Defenders | 20 | 05/15/2021 | Lancaster | USA | Right | Right | 6' 3" | 190 lbs | - |
| Swires, Wilson | RP | Chesterfield Queens | 23 | 08/28/2018 | Charlotte | USA | Right | Right | 6' 6" | 195 lbs | - |
