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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sakata, Masaaki | 3B | Free Agent | 28 | 09/22/2021 | Amagasaki | JPN | Right | Right | 6' 0" | 205 lbs | - |
| Sakowski, Adam | CF | Portland Pickles | 25 | 05/29/2024 | Columbia | USA | Right | Right | 6' 1" | 200 lbs | - |
| Salazar, Damian | C | Estes Park Elderhorns | 29 | 10/07/2020 | Carolina | PUR | Left | Right | 6' 1" | 205 lbs | $545,000 |
| Samples, Ryan | RP | Reno Copper Kings | 25 | 02/14/2025 | Jefferson City | USA | Left | Right | 6' 5" | 200 lbs | - |
| Sanchez, Bill | SP | Free Agent | 18 | 08/04/2031 | Santo Domingo | DOM | Right | Right | 6' 3" | 185 lbs | - |
| Sanchez, Efrain | RP | Reno Copper Kings | 25 | 12/12/2024 | Bethel CDP | USA | Left | Left | 6' 2" | 210 lbs | $545,000 |
| Sanchez, Miguel | SS | Reno Copper Kings | 27 | 07/09/2022 | Valle Hermoso | MEX | Right | Right | 6' 1" | 200 lbs | $1,500,000 |
| Sandoval, Leo | C | Free Agent | 27 | 12/15/2022 | Jima Abajo | DOM | Right | Right | 6' 0" | 200 lbs | - |
| Sandoval, Roberto | 1B | Nephi Threshers | 22 | 09/22/2027 | San Juan | PUR | Left | Right | 6' 7" | 200 lbs | - |
| Saunders, Erik | CF | Memphis BBQ | 22 | 08/10/2027 | Walnut Creek | USA | Left | Left | 6' 2" | 200 lbs | - |
| Saxton, Kevin | CF | Rochester River Sharks | 23 | 07/10/2026 | Santa Ana | USA | Right | Right | 6' 2" | 180 lbs | - |
| Sayadian, Gregory | SP | Ho Chi Minh City Tigers | 24 | 11/19/2025 | Hamilton | USA | Right | Right | 6' 5" | 200 lbs | - |
| Sayles, Alex | 3B | Rochester River Sharks | 29 | 08/19/2020 | Mountain View (Santa Clara County) | USA | Left | Right | 6' 1" | 200 lbs | - |
| Schafer, Karl | C | LetterKenny Irish | 24 | 12/20/2025 | Havre | USA | Switch | Right | 6' 0" | 190 lbs | - |
| Schnabel, David | 3B | Free Agent | 28 | 05/23/2021 | Lawrence | USA | Right | Right | 6' 0" | 200 lbs | - |
| Scott, Jaden | CF | Philadelphia Avalanche | 29 | 01/05/2021 | Macon | USA | Right | Right | 6' 4" | 205 lbs | - |
| Scully, Brian | 1B | Eugene Exploding Whales | 25 | 10/08/2024 | The Woodlands | USA | Left | Right | 6' 1" | 185 lbs | - |
| Shirley, Prímio | SS | Kinsale Fisherman | 25 | 09/15/2024 | Ciudad Guayana | VEN | Right | Right | 6' 2" | 205 lbs | $545,000 |
| Shoemaker, Ryan | LF | Free Agent | 28 | 01/30/2022 | Fresno | USA | Right | Right | 6' 3" | 200 lbs | - |
| Silander, Jim | LF | Memphis BBQ | 28 | 04/04/2022 | Sackville | CAN | Left | Left | 6' 2" | 200 lbs | $545,000 |
| Simko, Mark | 1B | Nephi Threshers | 22 | 09/04/2027 | Kechi | USA | Switch | Right | 6' 1" | 190 lbs | - |
| Simms, Korey | C | Thousand Oaks Rabbits | 23 | 10/15/2026 | Newark | USA | Switch | Right | 6' 1" | 200 lbs | $545,000 |
| Sivak, Vendelin | SP | Eugene Exploding Whales | 22 | 09/01/2027 | Hyattsville | USA | Right | Left | 6' 1" | 180 lbs | $545,000 |
| Skibbe, Mark | SP | Portland Pickles | 24 | 05/23/2025 | Manteca | USA | Right | Right | 6' 1" | 190 lbs | - |
| Sleezer, Brad | CL | Ho Chi Minh City Tigers | 22 | 02/03/2028 | Weston | USA | Switch | Right | 5' 11" | 175 lbs | $545,000 |
| Solis, Agustin | C | LetterKenny Irish | 23 | 06/23/2026 | Santo Domingo | DOM | Right | Right | 6' 4" | 205 lbs | - |
| Soto, Alexis | LF | Free Agent | 28 | 04/30/2022 | Los Teques | VEN | Right | Right | 6' 1" | 200 lbs | - |
| Spivey, Chris | SP | Phoenix Palisades | 24 | 07/27/2025 | Minneapolis | USA | Right | Right | 6' 4" | 200 lbs | - |
| Squillari, Jose | RP | Phoenix Palisades | 24 | 03/20/2026 | Anaco | VEN | Right | Right | 6' 2" | 195 lbs | - |
| Starks, Ryan | RP | Reno Copper Kings | 22 | 07/26/2027 | Sugar Hill | USA | Switch | Right | 6' 0" | 185 lbs | - |
| Stephen, Joey | 3B | Thousand Oaks Rabbits | 28 | 08/15/2021 | Apple Valley | USA | Right | Right | 6' 3" | 195 lbs | $545,000 |
| Stephens, Collin | 1B | Flint Coney Dogs | 28 | 08/22/2021 | Washington | USA | Left | Left | 6' 5" | 200 lbs | - |
| Stevenson, Tom | 2B | Estes Park Elderhorns | 24 | 08/12/2025 | Montreal | CAN | Right | Right | 6' 3" | 190 lbs | - |
| Stinney, Jayden | 3B | Free Agent | 26 | 09/26/2023 | Northwest Harbor | USA | Right | Right | 6' 0" | 205 lbs | - |
| Sturdivant, Justin | RP | Phoenix Palisades | 27 | 04/20/2023 | Ojus | USA | Right | Right | 6' 3" | 205 lbs | - |
| Sui, Yin-ti | SP | Free Agent | 33 | 08/10/2016 | Tsaotun | TPE | Left | Left | 6' 0" | 200 lbs | - |
| Sullivan, Nate | 3B | Free Agent | 26 | 04/15/2024 | Clemson | USA | Right | Right | 6' 2" | 205 lbs | - |
| Sutherland, Nick | SP | Portland Pickles | 23 | 11/22/2026 | Renton | USA | Right | Right | 6' 4" | 200 lbs | - |
| Swartz, Ralph | SP | Free Agent | 30 | 06/03/2019 | Monmouth | USA | Right | Right | 6' 6" | 200 lbs | - |
| Swerdlow, Larry | CL | Nephi Threshers | 23 | 09/11/2026 | Thunder Bay | CAN | Right | Right | 6' 3" | 200 lbs | - |
