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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Player | From-To | W | L | Pct | ERA | G | GS | CG | SHO | SV | IP | H | ER | HR | BB | SO |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mike Sacco | 2051-2051 | 0 | 2 | .000 | 7.83 | 5 | 5 | 0 | 0 | 0 | 23.0 | 30 | 20 | 6 | 10 | 15 |
| Jose Sanchez | 2044-2044 | 0 | 1 | .000 | 6.75 | 3 | 0 | 0 | 0 | 2 | 9.1 | 6 | 7 | 2 | 3 | 12 |
| Enrique Sandoval | 2035-2036 | 2 | 0 | 1.000 | 4.82 | 17 | 0 | 0 | 0 | 1 | 37.1 | 36 | 20 | 7 | 14 | 23 |
| Jason Schafer | 2051-2051 | 0 | 3 | .000 | 10.30 | 7 | 6 | 0 | 0 | 0 | 25.1 | 37 | 29 | 9 | 20 | 21 |
| Chris Schlichting | 2051-2051 | 1 | 0 | 1.000 | 5.52 | 10 | 4 | 0 | 0 | 1 | 31.0 | 33 | 19 | 7 | 16 | 35 |
| Ben Schuman | 2051-2051 | 3 | 3 | .500 | 11.68 | 10 | 4 | 0 | 0 | 0 | 24.2 | 33 | 32 | 8 | 15 | 18 |
| Josh Selby | 2035-2035 | 0 | 2 | .000 | 12.96 | 9 | 0 | 0 | 0 | 0 | 8.1 | 10 | 12 | 2 | 13 | 6 |
| Josh Semmons | 2051-2051 | 3 | 5 | .375 | 25.94 | 23 | 0 | 0 | 0 | 1 | 34.0 | 90 | 98 | 19 | 49 | 28 |
| Luke Senz | 2046-2046 | 1 | 2 | .333 | 2.45 | 12 | 0 | 0 | 0 | 6 | 14.2 | 13 | 4 | 3 | 2 | 21 |
| Chris Shewey | 2049-2049 | 5 | 0 | 1.000 | 2.27 | 7 | 7 | 0 | 0 | 0 | 39.2 | 31 | 10 | 1 | 10 | 49 |
| Dustin Shine | 2051-2051 | 1 | 2 | .333 | 13.94 | 24 | 0 | 0 | 0 | 0 | 20.2 | 43 | 32 | 3 | 23 | 18 |
| J.J. Shoemaker | 2051-2051 | 0 | 0 | .000 | 6.75 | 2 | 0 | 0 | 0 | 0 | 5.1 | 9 | 4 | 0 | 2 | 1 |
| Brad Sleezer | 2050-2050 | 6 | 0 | 1.000 | 0.68 | 7 | 7 | 1 | 0 | 0 | 52.2 | 28 | 4 | 1 | 15 | 39 |
| Joe Staley | 2048-2048 | 0 | 0 | .000 | 3.18 | 4 | 0 | 0 | 0 | 0 | 5.2 | 4 | 2 | 1 | 3 | 6 |
| Adam Stallard | 2051-2051 | 0 | 0 | .000 | 6.14 | 4 | 0 | 0 | 0 | 0 | 7.1 | 5 | 5 | 1 | 4 | 6 |
| Greg Sweigart | 2048-2049 | 0 | 0 | .000 | 4.80 | 9 | 0 | 0 | 0 | 2 | 15.0 | 13 | 8 | 3 | 3 | 12 |
